Semax and Selank: cognitive and anxiolytic peptides
Medically reviewed by: Op. Dr. Ferhat İlen, ENT – Head & Neck Surgeon · Last updated:
Semax is derived from a fragment of the ACTH hormone, while Selank is an analogue of the peptide tuftsin. In Russia, they are used post-stroke (Semax) and for anxiety (Selank); however, large controlled clinical trials meeting Western regulatory standards are lacking.
Regulatory / evidence status: Licensed in Russia; not approved by the FDA or EMA. Not licensed in Turkey.
Semax
Animal studies have reported increased BDNF expression and neuroprotection; it is administered as a nasal spray.
Selank
Small Russian clinical studies have reported positive effects in generalized anxiety disorder. It is claimed to be non-addictive, but independent validating data remain limited.
The Fi Life approach
In managing focus and stress, our priority is evaluating sleep, thyroid function, iron, vitamin B12, hormone profiles, and screening for sleep apnea; ENT expertise is utilized to specifically evaluate nasal and respiratory causes of sleep disruption.
Frequently asked questions
Will Semax show up on a drug test?
Although not explicitly named on the WADA Prohibited List, it may fall under the category of non-approved substances.
References
This page is for information only and does not replace diagnosis, treatment advice or a prescription. Peptide and drug assessments are made only after a physician consultation. No results are guaranteed.
Ask your physician whether it is right for you